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Histological analysis on day 7 revealed a significant decrease in the expression of proinflammatory cytokines in the wound, including TNF- and IL-6 in the D-CuP groups, accompanied by an increase in IL-10 expression (Fig

Furthermore, recent studies have highlighted the role of PS in activating key signal transduction pathways and regulating receptor function, renewing interest in its correlation with brain function

Chelating agents Because of the chemical similarities between Mn and Fe, it is possible that the neurotoxic effects of Mn might be associated with competition with Fe for non-redox domains in proteins [193]